mapping of transcription factor binding region of kappa casein (csn3) gene in iranian bacterianus and dromedaries camels

Authors

a.a. khabiri

m. tahmoorespur

m.r. nassiri

m.h. sekhavati

abstract

κ-casein is a glycosilated protein in mammalian milk that plays an essential role in the milk micelles. control of κ-casein expression reflects this essential role, although an understanding of the mechanisms involved lags behind that of the other milk protein genes. transcriptional regulation, a first mechanism for controlling the development of organisms, is carried out by transcription factors binding sites (tfbss).  we determined the 5’ region for iranian dromedaries and bactrianus camel κ-casein gene. we also determine their regulatory tfbss regions. this region contained 14 potential tfbss the four of them c/ebp-α, oct1, mgf/stat5 and tpb have almost perfectly conserved.

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Journal title:
international journal of advanced biological and biomedical research

Publisher: casrp publishing company

ISSN 2383-2762

volume 2

issue 5 2014

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